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MEDICINE_1O1 on Instagram: "Cullen’s Sign — periumbilical ecchymosis due to retroperitoneal bleeding. It occurs when pancreatic enzymes (especially in acute pancreatitis) cause fat necrosis and vessel erosion, allowing blood to track through fascial planes to the umbilicus. Cullen’s Sign often appears 24–48 hours after the onset of bleeding, so its presence usually indicates severe or delayed pathology. #neetpg #inicet #mbbs #medicine #fmge #doctor #studygram #medicos #usmle #studynotes"
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