How Digoxin acts as Cardiotonic in Heart Failure?
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How Digoxin acts as Cardiotonic in Heart Failure?
Digoxin increases force but decreases rate of contraction of heart. So it is specifically a cardiotonic with opposite action on the rate. It inhibits Na+/K+-ATPase pump thereby increases intracellular calcium levels which are responsible for increase in the force of contraction. The inhibitory effect on cardiac rate by Digoxin is due to its ...
46.5K viewsNov 4, 2019
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