The meaning of LOCO is in the register as written —used as a direction in music.

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loco in British English (ˈləʊkəʊ ) adjective denoting a price for goods, esp goods to be exported, that are in a place specified or known, the buyer being responsible for all transport charges from that place

Translate Loco. See 15 authoritative translations of Loco in English with example sentences, phrases and audio pronunciations.

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(Definition of loco from the Cambridge Advanced Learner's Dictionary & Thesaurus © Cambridge University Press)

(Commerce) denoting a price for goods, esp goods to be exported, that are in a place specified or known, the buyer being responsible for all transport charges from that place: loco Bristol; a loco price.