On "This Week," Cardinal Cupich said Pope Leo XIV may call for changes to the United States immigration system.

Cardinal Blase Cupich, Archbishop of Chicago, said he expects Pope Leo XIV "feels an obligation," to speak to what he called the issues of the day, amid "real challenges globally."

Leo XIV held his first Mass as pope in the Sistine Chapel on Friday, in what was a private service for the 132 voting cardinals who elected him as the 267th leader of the world’s 1.4 billion Catholics a day earlier.

Catholic cardinals gathered at the Vatican this week to elect the successor to Pope Francis, who died on April 21.

Leo gave a prepared address and then opened the floor to any cardinal who wanted to make a comment, a different format to what previous popes have done.

The contrast between President Trump and Chicago-born Pope Leo XIV couldn’t be more stark, politically, personally, or in their world views.

Pope Leo XIV asked journalists to be peacemakers by shunning prejudice and anger in their reporting, and he called for the release of journalists imprisoned for their work.

Pope Leo XIV is now the most powerful American Catholic in the world, and experts say he must aptly walk the line between U.S. politics and his papal duties.