The San Francisco 49ers can breathe a sigh of relief following the latest update on Isaac Guerendo’s injury status. However, ...

The 49ers lost their standout rookie Isaac Guerendo in scary fashion. What update did the running back provide Monday?

San Francisco 49ers rookie RB Isaac Guerendo suffered MCL and ankle sprains against the Arizona Cardinals, avoiding an ACL injury.

The season from the abyss is finally over for the San Francisco 49ers. They suffered a blowout loss to the Arizona Cardinals, ...

An MRI exam on Monday morning revealed that San Francisco 49ers rookie running back Isaac Guerendo (ankle, knee) suffered an ...

Rookie Isaac Guerendo battled injuries himself after taking the lead role in the backfield, and was carted off during the ...

After three straight seasons of long playoff runs, the San Francisco 49ers are packing up and heading home early for a change ...

The San Francisco 49ers announced they have signed OL Isaac Alarcon, WR Russell Gage, WR Isaiah Hodgins and T Jalen McKenzie ...