Knowing which lysosomal proteins are enriched in which brain cell types will help better understand contribution to neurological disorders.
Functioning brain cells need a functioning system for picking up the trash and sorting the recycling. But when the cellular ...
Together with colleagues from Stanford University, USA, researchers at the Leibniz Institute on Aging - Fritz Lipmann Institute (FLI) have, for the first time, created a comprehensive cell ...
Cell-type resolved protein atlas of brain lysosomes identifies SLC45A1-associated disease as a lysosomal disorder. Ali Ghoochani, Julia C. Heiby, Eshaan S. Rawat, Uche N. Medoh, Domenico Di Fraia, ...
Background: The pathogenesis of ulcerative colitis (UC) involves genetic susceptibility and immune dysregulation. However, a more comprehensive understanding of its underlying mechanisms is still ...
When the cell's recycling stations, the lysosomes, start leaking, it can become dangerous. Toxic waste risks spreading and damaging the cell. Now, researchers at Umeå University have revealed the ...
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