Knowing which lysosomal proteins are enriched in which brain cell types will help better understand contribution to neurological disorders.

Cell-type resolved protein atlas of brain lysosomes identifies SLC45A1-associated disease as a lysosomal disorder. Ali Ghoochani, Julia C. Heiby, Eshaan S. Rawat, Uche N. Medoh, Domenico Di Fraia, ...

Together with colleagues from Stanford University, USA, researchers at the Leibniz Institute on Aging - Fritz Lipmann Institute (FLI) have, for the first time, created a comprehensive cell ...

Companion studies suggest muscle begins to decline decades before sarcopenia takes hold for keeps. The best part: The process ...

Familial Hypobetalipoproteinemia (FHBL), caused by variants in the apolipoprotein B (APOB) gene, is a rare autosomal ...

Illinois couple Megan Kempf and Kyle are parents to Poppy, 9, and Oliver, 2, who suffer from a dementia-like condition called ...

Meng Wang got hooked on aging research during her postdoc days at Harvard and Mass General. Like many of us, she noticed how some folks just keep going strong while others fade earlier. Drawing from ...

When the cell's recycling stations, the lysosomes, start leaking, it can become dangerous. Toxic waste risks spreading and damaging the cell. Now, researchers at Umeå University have revealed the ...