ABSTRACT: Amphiphilic triblock poloxamer 188 (P188) has demonstrated its therapeutic potential for muscle, cardiac and neurological injuries. While this surfactant is thought to primarily reseal the ...
Furthermore, by using tissue sections, we accurately assessed cardiomyocyte ploidy changes post-TAC by measuring their nuclear volume, revealing that polyploid cells constituted 13.15% in Sham hearts ...
Abstract: The purpose of the present study was to determine the alterations of contraction parameters in isolated cardiomyocytes under anoxia and reoxygenation by using a video tracking system ...
Diastolic dysfunction is central to diseases such as heart failure with preserved ejection fraction and hypertrophic cardiomyopathy (HCM). However, therapies that improve cardiac relaxation are scarce ...
Regulation of sodium flux across the cell membrane plays a vital role in the generation of action potentials and regulation of membrane excitability in cells such as cardiomyocytes and neurons.
The measurement of the contractile behavior of single cardiomyocytes has made a significant contribution to our understanding of the physiology and pathophysiology of the myocardium. However, the ...
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