New research from an international team of plant biologists, led by researchers at the VIB-UGent Center for Plant Systems Biology, has revealed crucial insights into the role brassinosteroids – ...

The intrinsic factor of cell senescence, PCBP2, was identified by unlabeled quantitative proteomics, and its biological role in in vitro replication senescence of human bone marrow mesenchymal stromal ...

Azenosertib median duration of response (mDOR) updated to 6.3 months in the ongoing DENALI Part 1b clinical trial in patients with platinum-resistant ovarian cancer (PROC) and continues to demonstrate ...

the compound induced cell cycle arrest: in SW-480 and Caco-2 cells, it halted progression at the S phase through the ATR/Chk1 pathway, while in HCT-116 cells, it caused arrest at the G1 phase via ...

A77 1726 inhibits tyrosine kinases responsible for early T cell and B cell signalling in the G 0 /G 1 phase of the cell cycle. Because the immunoregulatory effects of A77 1726 occur at doses that ...

Experiments included testicular transcriptome analysis, sperm metabolomics, sperm motility and fertilization assays, embryonic ROS detection, and RNA sequencing of 2-cell embryos ... egg were ...

Using single-cell RNA sequencing, we mapped thousands of expression quantitative trait loci in yeast, including a variant in GPA1 that influences gene expression, cell-cycle occupancy, and mating ...

Neuroblastoma (NB), the most prevalent extracranial solid tumor among children, is characterized by a high rate of metastasis ...