Every time a cell divides, it must copy its DNA with extraordinary precision. But this process is constantly challenged by ...

A subtle failure during cell division can set off dramatically different outcomes, according to new research exploring whole genome duplication. A new study finds that the way a cell fails to divide ...

In the small Tuscan town of Vinci, inside church tombs that have held bones for centuries, researchers recently extracted ...

Loss of an enzyme necessary for a process called lipoylation disrupts the way cancer cells copy their DNA, increasing their ...

From the first unzip of the double helix to the final joining of DNA fragments, replication is a carefully coordinated process. Understanding it helps explain how life preserves its genetic code with ...

Scientists have taken an important step toward a gene therapy that could one day turn off the extra genetic material that causes Down syndrome (DS). Down syndrome is a genetic condition caused by an ...

Before a cell can divide, it has to precisely duplicate its entire genetic information. However, the DNA in the cell exists as part of a DNA-protein complex known as chromatin. For this purpose, the ...

When bacteria cells replicate, they do so a little differently than human cells do. They don't undergo mitosis, a splitting that involves construction of spindles to carefully separate the DNA after ...

Top: Chromosome separate with functioning SMC in two models, line drawing and filled-space. The red and pink dots indicate, respectively, ori on each copy of DNA. Bottom: DNA separating without ...

A simulated cell in the early stages of division. Left half shows cytoplasm (blue cubes), mRNA degradation machinery molecules (pink), and sugar transporters (brown). Right half adds the membrane ...

The researchers, led by chemistry professor Zan Luthey-Schulten at the University of Illinois Urbana-Champaign, present their findings in the journal Cell. In two videos, researchers describe the work ...

Men tend to lose the Y chromosome from their cells as they age. But because the Y bears few genes other than for male determination, it was thought this loss would not affect health. But evidence has ...