Discover the bold trade the St. Louis Cardinals must make before the 2025 MLB deadline to jumpstart their next championship run.

The St. Louis Cardinals didn't fully blow it up ahead of the 2025 Major League Baseball trade deadline, but it did sell off some pieces. With the club's playoff hopes taking a nosedive since the All-Star break,

The St. Louis Cardinals (55-55) visit the San Diego Padres (60-49) open a 3-game series Friday at Petco Park. First pitch is scheduled for 9:40 p.m. ET. Let's analyze BetMGM Sportsbook's MLB odds around the Cardinals vs. Padres odds and make our expert MLB picks and predictions for the best bets.

The Miami Marlins (51-55) and the St. Louis Cardinals (55-54) wrap up a 3-game series Wednesday. First pitch from Busch Stadium is scheduled for 7:45 p.m. ET (MLB.TV Free Game of the Day). Let's analyze BetMGM Sportsbook's MLB odds around the Marlins vs. Cardinals odds and make our expert MLB picks and predictions for the best bets.

The starting pitchers are Randy Vasquez (3-4) for the San Diego Padres, and Michael McGreevy (2-2) for the St. Louis Cardinals. The Padres won their last game against the Mets on Wednesday by a 5-0 score.

But, the next day, as Katie Woo of The Athletic reports, the Cardinals are losing Arenado to the injured list with a shoulder issue. He'll go on the 10-day injured list, as Nolan Gorman is activated in his place.