Methamphetamine doesn't just spike levels of the pleasure-inducing hormone dopamine in the reward pathways of the brain—it ...

Rutgers researchers have used neuroimaging to demonstrate that cocaine addiction alters the brain's system for evaluating how rewarding various outcomes associated ...

Methamphetamine addiction has long been framed as a story of dopamine gone haywire, with the drug flooding the brain’s reward ...

Neuroscientists find that two distinct neural pathways are responsible for the addictive properties of the opioid fentanyl: one mediates reward, the other promotes the seeking of relief from symptoms ...

Why do so many people relapse after quitting cocaine? A new study from The Hebrew University reveals that a specific "anti-reward" brain circuit becomes hyperactive during withdrawal-driving ...

Harold Lewis has been fighting drug addiction for years, but only recently started thinking recovery could be fun. The 59-year-old former cook earned small prizes -- candy, gum, gift cards, sunglasses ...

Addiction is one of the most intensely studied conditions in modern medicine, yet even with high‑resolution brain scans and genetic tools, scientists still cannot fully explain why some people get ...