Bivalent EABR mRNA boosters broaden neutralizing responses to Omicron subvariants by promoting diverse receptor-binding domain epitope targeting, although antibody responses remain partially shaped by ...
In this study in silico docking models were employed to investigate the molecular interactions between the receptor-binding domain (RBD) of the SARS-CoV-2 spike glycoprotein, derived from the ...
Researchers at Mount Sinai have produced high‑resolution structural maps of antibodies generated after initial mRNA COVID‑19 vaccination, revealing why some lose potency against evolving SARS‑CoV‑2 ...
Mentor(s): Michael Kennedy, Ph.D. Understanding binding of animal rotavirus strains offers insight into zoonotic potential The goal of this project is to determine if bat P[10] binds in an excited ...
Converge Bio, the Generative AI Lab for the Life Sciences, shares findings from a new study showing that ConvergeAB™, their antibody design and optimization solution, was able to improve cetuximab, a ...
The right approaches are demonstrating that it is possible to breach the defensively designed blood-brain barrier despite its ...
A new study designs drugs that bind to intrinsically disordered proteins that are extremely difficult to target due to their flexible nature.
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