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What are Hidden RNAs and How Can You Identify Them in RNA-Seq Data?

Produced in Partnership with RNA ConnectReviewed by Maria OsipovaOct 10 2025 The UltraMarathonRT ® cDNA Synthesis and Amplification Kit delivers a comprehensive approach for copying polyA+ RNA into ...
eLife

TSvelo: Comprehensive RNA velocity by modeling the cascade of gene regulation, transcription and splicing

This study presents a valuable tool named TSvelo, a computational framework for RNA velocity inference that models transcriptional regulation and gene-specific splicing. The evidence supporting the ...
ascopubs.org

Identification and Validation of Prognostic Model for Tumor Microenvironment-Associated Genes in Bladder Cancer Based on Single-Cell RNA Sequencing Data Sets

Combined Transcriptome and Circulating Tumor DNA Longitudinal Biomarker Analysis Associates With Clinical Outcomes in Advanced Solid Tumors Treated With Pembrolizumab The prognostic model demonstrated ...
EurekAlert!

Single-Cell RNA-seq reveals transcriptomic modulation of Alzheimer’s disease by activated protein C

“We believe our study utilizing Single-Cell RNA sequencing will provide additional rationale towards the effects on APC treatment observed in previous studies on 5xFAD AD mice.” “In our investigation, ...
ascopubs.org

5-Hydroxymethylcytosine Profiling of Cell-Free DNA Identifies Bivalent Genes That Are Prognostic of Survival in High-Risk Neuroblastoma

Validation of the Combined Clinical Cell-Cycle Risk Score to Prognosticate Early Prostate Cancer Metastasis From Biopsy Specimens and Comparison With Other Routinely Used Risk Classifiers 5-hmC ...