Scientists have traced connectivity between neurons to identify how the brain communicates with the spinal cord. A new brain map visualizes the connections between the brain and spinal cord at the ...

A cellular recycling system called CMA was found to be impaired in ALS motor neurons. Reduced CMA activity was linked to TDP-43 protein clumps, a hallmark of most ALS cases. Boosting CMA may be a ...

Motor neurons innervate muscle cells to control various voluntary and involuntary movements. The progressive degeneration of motor neurons is the core of neuromuscular disorders, such as ALS. AxoCells ...

Researchers at UC Santa Barbara are coming ever closer to uncovering the neural circuitry that translates stimulus to action, shining light on previously unseen neural connections and lesser-known ...

Intracellular transport is a vital process that allows cells to move proteins and other molecules to specific locations. This process is especially important in neurons, which have highly polarized ...

Researchers have developed a gene therapy that significantly slowed motor function loss in preclinical models of amyotrophic lateral sclerosis (ALS), offering new hope for treating the devastating ...

Scientists at the University of Washington and Harvard Medical School, in collaboration with the ESRF, have discovered the neural circuits that coordinate leg and wing movements in the fruit fly ...

Scientists traced connectivity between neurons to identify how the brain communicates with the spinal cord to control motor function. Signals relayed to motor neurons from the brain enable muscle ...