Study shows how telomerase can run amok, deleteriously capping damaged DNA, were it not for a first responder to DNA damage. The natural ends of chromosomes appear alarmingly like broken DNA, much as ...

September 3, 2008 — It has been suggested that telomeres and telomerase are therapeutic targets in oncology, but many gaps remain in the understanding of their basic biology. However, in a study ...

Researchers at Arizona State University’s (ASU) School of Molecular Sciences and the Biodesign Institute’s Center for the Mechanism of Evolution have discovered an unprecedented pathway producing ...

Our DNA is organized into chromosomes, and the ends of chromosomes are protected with caps called telomeres; when cells divide, they lose a very small amount of DNA from those ends. Short telomeres ...

Although most of us accept aging as a natural part of life, it might not have to be. Researchers at UC Berkeley have now mapped out the structure of telomerase – an enzyme known to play a key role in ...

New research from the University of Maryland and the National Institutes of Health reveals a new role for the enzyme telomerase. Telomerase's only known role in normal tissue was to protect certain ...

Negative results and findings in science are perhaps less newsworthy, but they are no less important. Particularly when, as in this case, they demonstrate that a possible new therapeutic pathway ...

Nothing in your body lasts forever. Every single cell in your body will die eventually, and eventually you’ll run out of replacements. When that happens, various parts of your body will stop working ...

A structural model of the telomerase enzyme shows how the binding domain (purple) tethers one end of the RNA component of the enzyme. (Image credit: Jansson et al., ) Researchers at UC Santa Cruz have ...

Science has identified in the plant kingdom the “missing link” of cellular immortality between human and single-celled animals, according to a new study led by scientists from Arizona State University ...