Since it went on the market, the newer device has been the subject of several reports of hemolysis. This would seem ...

AJMC ®: Paroxysmal nocturnal hemoglobinuria (PNH) is 1 of several complement-driven diseases. Can you describe its clinical presentation? DE CASTRO: PNH presents heterogeneously. One of the 3 ...

"Our previous work showed that SARS-CoV-2 spike proteins lead to complement dysregulation by binding heparan sulfate and disrupting complement factor H…This doesn’t happen on red cells because red ...

Physical/chemical causes. These causes of hemolysis are most often secondary to improper handling of blood products. Reasons include inadvertent heating or freezing with subsequent thawing of the red ...

The phase 3 PEGASUS trial found that patients with paroxysmal nocturnal hemoglobinuria (PNH) may still experience anemia following recommended therapies, underscoring the need for further research. In ...