Japanese scientists have developed a new method for DNA amplification and sequencing that improves the accuracy of single-cell RNA sequencing (scRNA-seq). The new method called TAS-Seq uses a terminal ...

There’s been this dream for decades. What if we could just print out an entire gene directly, one base at a time? —Daniel Lin-Arlow, Ansa Biotechnologies As scientists set their sights on cell and ...

Expertise from Forbes Councils members, operated under license. Opinions expressed are those of the author. DNA synthesis is vital to several processes in biopharmaceutical innovation, including the ...

Thymosin (fraction 5 and synthetic α 1 peptide) induced prothymocytes in mouse bone marrow and spleen to express terminal deoxynucleotidyl transferase (TdT; DNA nucleotidylexotransferase; ...

In terms of efficiency, the phosphoramidite method used for synthesizing DNA oligonucleotides is hard to top. Each base-adding step achieves a 99.5% yield. But the method still can’t produce sequences ...

To clarify the functions of the Arabidopsis thaliana REV1 (AtREV1) protein, we expressed it in Escherichia coli and purified it to near homogeneity. The deoxynucleotidyl transferase activity of the ...

We have created double-stranded oligonucleotide arrays to perform highly parallel investigations of DNA–protein interactions. Arrays of single-stranded DNA oligonucleotides, synthesized by a ...

How did the idea of recombinant protein emerge? Recombinant proteins were proposed by Peter Lobban who was the first person to produce and replicate recombinant DNA in 1972 and 1973. The recombinant ...