Monitoring and maintaining a higher tacrolimus trough level in the first month after transplantation is essential to avoid acute rejection, according to investigators. Maintaining a tacrolimus trough ...

Kidney transplant recipients typically take the immunosuppressant drug tacrolimus to prevent rejection, and some patients experience large fluctuations in blood levels of tacrolimus even when the dose ...

Please provide your email address to receive an email when new articles are posted on . In a retrospective pediatric cohort study, researchers observed 426 patients who underwent kidney-only ...

Tucson, AZ - Tacrolimus (Prograf, FK506, Fujisawa Healthcare Inc) is safe and well tolerated and provides clinical benefit lasting at least 12 months in rheumatoid arthritis (RA), according to a new ...

Tacrolimus is a mainstay immunosuppressant used to prevent rejection in kidney transplant recipients. However, its narrow therapeutic index necessitates routine monitoring, as intrapatient variability ...

In paediatric kidney transplant recipients, high variability in tacrolimus trough blood levels was significantly associated with allograft rejection occurring beyond 12 months post-transplant; however ...

Getty Images Nephrotoxicity remains a major concern with the use of calcineurin inhibitors. Adding the calcineurin inhibitor tacrolimus to standard immunosuppression may further reduce proteinuria in ...