Loss and dysfunction of synapses have been linked to age-related cognitive decline and observed in Alzheimer's and other ...

Astrocytes use the MEGF10 receptor to prune synapses in the striatum, a process essential for dopamine-driven motor learning.

In the Alzheimer’s disease brain, synaptic loss correlates with cognitive decline, and is considered a sign of disease progression. But is synaptic loss always bad? Provocative new data from several ...

Francesca has an MSci in Biochemistry from the University of Birmingham.View full profile Francesca has an MSci in Biochemistry from the University of Birmingham. Use it or lose it – that’s the motto ...

Neurofibrillary tangles, the hallmark of tauopathies, are closely linked to failing cognition. So are tau oligomers, suggest scientists led by Teresa Gómez-Isla at Massachusetts General Hospital in ...

Welcome back to Birdbrained Science! Last time, we touched on the ‘bird’ aspect with migration and today, we’ll cover some brain stuff — let’s talk about pruning. However it happens, we know that once ...

As we age, we begin to lose the connections that wire up our brains-and neuroscientists aren't sure why. It is increasingly clear, though, that the loss of synapses-the flexible and adaptive relay ...