Understanding the impact that subtle variations (missense mutation, environmental change, ion chelation, ligand binding, etc.) have on protein structure helps to reveal their biological effects, but ...
On Wednesday, the Nobel Committee announced that it had awarded the Nobel Prize in chemistry to researchers who pioneered major breakthroughs in computational chemistry. These include two researchers ...
In the wee hours of an October morning, David Baker, a protein biologist at the University of Washington (UW), received the most-awaited phone call in a scientist’s career. Halfway around the world, ...
Half the prize goes to Demis Hassabis and John M. Jumper from Google DeepMind for using AI to solve protein folding, and the other to David Baker for tools to help design new proteins. In a second ...
Accurately building 3D atomic structures from cryo-EM density maps is a crucial step in cryo-EM-based protein structure determination. Converting density maps into 3D atomic structures for proteins ...
An international research team led by a Korean scientist has succeeded in designing large-scale protein structures that faithfully replicate the ...