PET imaging of reactive astrocyte-neuron interaction reveals new insights into Alzheimer's disease pathology, offering a potential breakthrough in diagnosis and treatment Recently, a team of South ...

Scientists have discovered a way to help the brain clean itself of harmful Alzheimer’s plaques by activating its own support cells. By increasing a protein called Sox9, researchers were able to boost ...

In neurodegenerative diseases such as Alzheimer’s, Parkinson’s, and ALS, excessive H2O2 from reactive astrocytes triggers a vicious cycle of oxidative stress, protein aggregation, and neuronal loss.

Once overlooked, astrocytes are increasingly recognized as star players in Alzheimer’s disease, with recent studies blaming them for feeding into a neurotoxic stew that kills neurons. In the September ...

A new platform for screening astrocyte reactivity helps researchers uncover potential therapeutic interventions to treat neurodegenerative conditions. Led by postdoctoral researcher Benjamin Clayton, ...

Much of the brain is made up of a constellation of star-shaped cells called astrocytes, which play vital roles in immunity, neuron maintenance and many other functions. In Alzheimer’s disease, some ...

When the brain is injured in some way, a wide range of biochemical changes are triggered that can affect crucial brain cells known as astrocytes. They are a type of glial cell, and brain injuries ...

Every stroke begins with a sudden interruption of blood flow in the brain. But what happens afterward—why neurons continue to ...

The potential effects of astrocyte dysfunction in neurodegenerative diseases are summarized in Figure 2. AD is characterized clinically by cognitive loss in two or more domains, including memory, ...

Past neuroscience studies found that when the central nervous system (CNS) is damaged, for instance following a stroke or spinal cord injuries, the lesions become surrounded by borders of newly ...