TRIBE method for identifying RNAs that interact with ribosome-binding proteins (RBPs) fuses an RBP of interest to the catalytic domain (CD) of an RNA-editing enzyme. When the RBP-CD fusion protein ...
A new method developed at Baylor College of Medicine and collaborating institutions allows researchers to better understand how RNA works. The method is a powerful strategy for identifying intricate ...
The field of neurodegenerative disease research has increasingly focused on the roles of RNA-binding proteins in the pathogenesis of amyotrophic lateral ...
This manuscript has convincing data that provides a high-resolution structure of the Egl-RNA complex. The findings are important to understand the formation, stability, and interactions of this ...
A new biochemical method identifies RNA 3D structures and protein binding sites in cells. It reveals how RNA folding drives ...
In this valuable study, the authors develop new approaches to investigate mRNA imprinting, a phenomenon in which RNA-protein complexes form in the nucleus to influence the fate of transcripts in the ...
Researchers at the University of Toronto have shown that an important class of DNA-binding factors can also bind to RNA, regulating gene expression through various mechanisms. The study significantly ...
Artificial intelligence (AI) -powered H&E whole-slide image (WSI) analysis of tertiary lymphoid structure (TLS) to predict response to immunotherapy in non-small cell lung cancer (NSCLC). Molecularly ...
A new method developed at Baylor College of Medicine and collaborating institutions allows researchers to better understand ...