An international research team has uncovered a new mechanism crucial to the production of cellular proteins. When this mechanism is disrupted, the blueprints used by the cell to produce proteins are ...
An international research team has uncovered a new mechanism crucial to the production of cellular proteins. When this mechanism is disrupted, the blueprints used by the cell to produce proteins are ...
Misshapen proteins cause a mess of trouble—particularly in neurodegenerative diseases. But a new study suggests it's possible ...
A Purdue University research team has revealed complex new details about the function of a key protein shared by mammals, including humans. Many cancers result when this DNA methyltransferase protein ...
Bodybuilders and cellular mechanisms agree generating protein is a heavy lift. To complete the task, cells rely on complexes called spliceosomes. These molecular machines snip extra bits out of our ...
The student will investigate how protein arginine methylation, a type of post-translational modification commonly found in RNA-binding proteins, regulates the function of an evolutionarily conserved ...
Why do problems occur with a special variant of 'protein glues', the split inteins, that severely limit their use in producing proteins? A team has now answered this question. Proteins are the ...
Alternative splicing is a genetic process where different segments of genes are removed, and the remaining pieces are joined together during transcription to messenger RNA (mRNA). This mechanism ...
This article was review by Thomas Cooper, MD from Baylor College of Medicine. Stay up to date on the latest science with Brush Up Summaries. Despite its significance, alternative splicing’s global ...
Misshapen proteins cause a mess of trouble-particularly in neurodegenerative diseases. But a new study suggests it's possible ...
USP39 stabilizes the spliceosome (green), which cuts out unneeded parts (grey and purple) of the mRNA. If USP39 is missing, some of the mRNA is poorly processed. This results in misfolded proteins, ...
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