Targeted protein degradation has moved well beyond its prologue more than 20 years ago. 1 The number of publications describing different PROTACs (PROteolysis TArgeting Chimeras), molecular glues, and ...

Targeted protein degradation (TPD) is a promising alternative to conventional small-molecule drugs. Rather than inhibiting a single enzyme’s function, degrader molecules label selected ...

The field of targeted protein degradation (TPD) is advancing at an unprecedented pace, offering novel therapeutic strategies for addressing previously undruggable targets. However, efficient and ...

This article and associated images are based on a poster originally authored by Tika R. Malla, Emma Mead and Emma J. Murphy and presented at ELRIG Drug Discovery 2024 in affiliation with University of ...

This article is based on a poster originally authored by Melanie Kelm et. al. ProteinSimple’s automated western blotting system, Jess, can be used in a range of applications, such as in drug discovery ...

Bioluminescent assays are essential tools for tracking protein activity, cell signaling pathways and cellular dynamics. These assays provide high sensitivity, low background noise, and flexibility for ...

Bio-Techne is proud to provide a first glimpse into the power and performance of the Leo™ System using several assay models as it hits the market. Data highlights include throughput, sensitivity, ...