Researchers at Baylor College of Medicine have developed a powerful new data analysis method named COOKIE-Pro (Covalent ...

Proteins perform their many different functions via physical interactions with other molecules, in particular, small ...

Using over 220,000 AI-predicted protein structures from the AlphaFold database and sophisticated computational pocket detection tools, bioinformaticians Hanne Zillmer and Dirk Walther identified ...

COOKIE-Pro precisely measures both the binding strength and reaction speed of drugs against thousands of potential targets simultaneously.

The ability to alter proteins to refine control over binding affinity and specificity can create tailored therapeutics with reduced side effects, highly sensitive diagnostic tools, efficient ...

Recombinant protein expression is a cornerstone of modern biotechnology, fueling advances in drug development, molecular ...

Scientists have created a breakthrough technology that reveals the entire network of RNA-protein interactions in human cells, offering new insights into how diseases develop.

Various approaches to such protein redesign have drawbacks. Traditional methods include time-consuming trial and error efforts, and many models in the emerging field ...