The Journal of Immunology reports that vaccination of neonatal mice with group A Streptococcus promoted a clonal expansion of innate-like B cells that produce antibody against N-acetyl-D-glucosamine, ...

Type 1 diabetes arises through autoimmune destruction of insulin‐producing pancreatic β‐cells. MicroRNAs (miRNAs) have emerged as critical regulators at the interface of immune activation and β‐cell ...

Pathophysiology of Diabetes Mellitus: Understanding the Process and Complications : By Shayak Sanyal Key InsightsDiabetes is one of the most complex types of chronic diseases, which can have long-term ...

Type 1 diabetes researcher Anette Ziegler has never believed the word impossible. Important steps in her career have been driven by a spirit of opening new paths and constantly pushing beyond ...

Researchers have discovered the novel mechanism that underlies a previously reported observation that infection by group A Streptococcus bacteria reduces the risk of later developing type 1 diabetes.

Vaccination of neonatal mice with group A Streptococcus promotes clonal expansion of B cells that produce antibody against GlcNAc. The association of reduced Type 1 diabetes risk after group A ...