The first 27-18 finish came on Sept. 10, 2000, when Rob Johnson led the Buffalo Bills to a home win over Brett Favre and the Packers. Although Favre went 25-of-35 for 269 yards and two touchdowns, Green Bay went just 2-of-12 on third down.

Cardinals head coach Jonathan Gannon, when asked about the losing streak and how the team is handling it, offered the following: "Probably as good as you can. They're not happy. They're not happy. We feel like we're right there. But to get in the win column, we got to do a little bit more," Gannon told reporters on Monday.

How was Sunday's performance from the Cardinals' offense different under QB Jacoby Brissett? Let's look into the numbers:

The Tennessee Titans fired head coach Brian Callahan, the first lead skipper to lose his job this year. He led the team to a 4-19 record, losing five of six games this season.

Although he was still forcing his way into the end zone, Green Bay Packers running back Josh Jacobs had been struggling to generate much efficiency as a ball-carrier entering a Week 6 matchup against the Cincinnati Bengals.

What channel is Arizona Cardinals vs Indianapolis Colts game on today? How to watch NFL Week 6 football game on TV, streaming Sunday, Oct. 12, 2025.

The Green Bay Packers weren’t appreciably healthier in their first game coming out of the bye. They left it significantly more injured. Three

Jacoby Brissett, filling in for an injured Kyler Murray, finished 27-for-44 for 320 yards and two touchdowns with one interception.