Besides the obvious physical and psychological aspects of dependency and addiction, is there any research documenting the effect of using long-term opioids (to treat chronic pain) on the body?

When you have a mild headache or muscle ache, an over-the-counter pain reliever is usually enough to make you feel better. But if your pain is more severe, your doctor might recommend something ...

Researchers at USF Health have discovered a new way opioid receptors can work that may lead to safer pain medications. Their findings show that certain experimental compounds can amplify pain relief ...

Millions of people take opioids for chronic back pain, but many of them get limited relief while experiencing side effects and worrying about the stigma associated with taking them, suggests research ...

Medically reviewed by Lindsay Cook, PharmD Key Takeaways Naloxone is a fast-acting drug used to reverse opioid ...

Opioids, such as oxycodone, morphine, codeine, tramadol and fentanyl, are commonly prescribed to manage pain. You might be given a prescription when experiencing pain, or after surgery or an injury.

New research about the harms of long-acting opioids may underestimate risks, members of two FDA advisory committees said Monday. Data did not represent large segments of the U.S. population and relied ...

Opioid medications will be required to have their labeling updated to highlight the safety risks of long-term use, the FDA announced on Thursday. The agency is requiring opioid manufacturers to add to ...

An experimental drug developed at Duke University School of Medicine could offer powerful pain relief without the dangerous side effects of opioids. The drug, called SBI-810, is part of a new ...

The new method is designed to focus specifically on pain-related signals, without interfering with normal activity in other parts of the brain. A new preclinical study has identified a gene therapy ap ...