When you have a mild headache or muscle ache, an over-the-counter pain reliever is usually enough to make you feel better. But if your pain is more severe, your doctor might recommend something ...

Researchers at USF Health have discovered a new way opioid receptors can work that may lead to safer pain medications. Their findings show that certain experimental compounds can amplify pain relief ...

Besides the obvious physical and psychological aspects of dependency and addiction, is there any research documenting the effect of using long-term opioids (to treat chronic pain) on the body?

Medications have become our go-to treatments for opioid addiction. Though life-saving, their downsides are underappreciated ...

New research reveals previously unknown ways opioid receptors can function, opening the door to safer pain treatments.

Chronic pain patients don’t fare much better taking opioids to manage their pain than they do by taking placebos, a study published recently in the Journal of the American Medical Association found.

A BMJ review finds tramadol offers minimal chronic pain relief but significantly increases serious side effects, especially heart-related risks.

New research about the harms of long-acting opioids may underestimate risks, members of two FDA advisory committees said Monday. Data did not represent large segments of the U.S. population and relied ...

Millions of people take opioids for chronic back pain, but many of them get limited relief while experiencing side effects and worrying about the stigma associated with taking them, suggests research ...

Scientists are racing to redesign how powerful painkillers work, aiming to keep the relief that opioids provide while ...

Dr Jagannathan highlighted five specific classes of drugs that patients and physicians should monitor closely for ...