Scientists have uncovered the intricate circuit cues behind neuronal cell maturation and migration, which is required for proper cognitive function. The journey of a thousand miles begins with a ...

New research has shown that Sonic Hedgehog (SHH)–Gli1 signaling in microglia amplifies inflammatory responses through the IKKβ/NF-κB pathway, contributing to dopaminergic neuron loss in Parkinson’s ...

Researchers at Tulane University, with a team of colleagues from eight other universities, have discovered a new nerve cell signaling mechanism that could transform our understanding of pain and lead ...

The researchers found that this process is triggered when a neuronal signal causes calcium to enter the dendrite through voltage-gated ion channel proteins, which are positioned at the contact sites.

A tiny strip of printed nanomaterials fired an electrical spike, and a living mouse brain cell answered back. That exchange, ...

New experiments reveal how astrocytes tune neuronal activity to modulate our mental and emotional states. The results suggest that neuron-only brain models, such as connectomes, leave out a crucial ...

As a neuromodulator, norepinephrine is a powerful force in the brain. We all know it orchestrates rapid changes in behavior such as the fight-or-flight response. Fewer people know that astrocytes ...

University of Pennsylvania and Syracuse University scientists have discovered that a hindbrain-derived peptide, octadecaneuropeptide (ODN), can suppress appetite and improve glucose regulation without ...