Indianapolis is a 9.5-point favorite in the latest Cardinals vs. Colts odds from SportsLine consensus, while the over/under for total points scored is 46.5. The Colts are -500 money line favorites (risk $500 to win $100),

How was Sunday's performance from the Cardinals' offense different under QB Jacoby Brissett? Let's look into the numbers:

League executives had different opinions on whether a fine for Cardinals coach Jonathan Gannon's outburst was warranted.

Murray missed two days of practice this week with a foot injury and was listed as questionable after returning for a limited workout on Friday. A report on Sunday morning indicated that he will miss the game and the Cardinals made it official 90 minutes ahead of their game in Indianapolis against the Colts.

Week 6 of the 2025 NFL season kicked off with a jaw-dropping upset. The New York Giants (2-4) shocked the defending Super Bowl LIX champion Philadelphia Eagles (4-2) in a 34-17 victory Thursday night.

The Athletic NFL insider Dianna Russini revealed what her sources across the league had to say about the Arizona Cardinals fining Jonathan Gannon.

ARIZONA -- Don't look now, but Arizona Cardinals rookie CB Will Johnson is playing at levels high enough to be considered one of the best in the NFL. According to Pro Football Focus, he is. PFF's grading system has Johnson as the No. 1 player at his position with a 84.5 overall grade entering Week 6.