A frequently reported fact in the drug discovery and development industry is that approximately 90 % of drug candidates reaching clinical trials fail, with even higher amounts discarded before ...

Traditional animal models and simplified cell cultures often fail to capture human biology, limiting progress in biomedical research and drug development. Emerging microfluidic "Organ-on-Chip" ...

The models can be used to plan surgeries and in the future could be used to help trial new drugs. A healthy heart beats at a steady rate, between 60 and 100 times a minute. That’s not the case for all ...

The synovium is a membrane-like structure that lines the knee joint and helps to keep the joint happy and healthy, mainly by producing and maintaining synovial fluid. Inflammation of this tissue is ...

Overcoming acquired treatment resistance is one of the major challenges in the fight against cancer. While combination therapies hold promise, their toxicity to healthy tissue remains a major hurdle.

Recent advancements in organoid structures have allowed scientists to culture complex collections of cells that mimic the architecture and functionality of a patient’s organs, imitating the ...

Biomedical engineers have developed a silk-based, ultrathin membrane that can be used in organ-on-a-chip models to better mimic the natural environment of cells and tissues within the body. When used ...