Nearly 100 years ago, a seemingly simple discovery revolutionized the microscope. The introduction of phase contrast, which garnered a Nobel Prize in 1953, brought into clear view structures inside ...

Imagine tuning into a football game, but all of the players are invisible except for the two quarterbacks. Without being able to see the orchestrated movements of the full teams, this would be a very ...

Bioengineers bridge the gap between spectroscopy developers and biologists through a systematic guide explaining modern Raman ...

These images show the high resolution achieved with the new microscopy technique. A mouse brain cross-section as seen with photoacoustic imaging is shown in the upper left image, with two detailed ...

uiPSF is a toolbox to measure point spread functions based on inverse modeling that improves single-molecule localization microscopy (SMLM) localization and microscope characterization, and that works ...

Scientists from the National Graphene Institute at the University of Manchester and Sun Yat-sen University have captured the ...

Cryo-electron microscopy (cryo-EM) can help scientists determine the three-dimensional structure of proteins in unprecedented detail. Jacques Dubochet, former group leader at EMBL, shared the 2017 ...

Stretching protein samples in all directions pulls molecules farther apart, allowing them to be visualized using only light ...

Fast piezo and voice-coil nano-focusing systems keep microscopes and metrology tools sharply focused with nanometer precision ...

Chemists discover how key contrast agent works, paving a way to create new markers needed for correlative microscopy that can image the structure and signaling of cells at the same time. Two labs at ...

A new computational microscopy technique solves for true high-resolution images without the guesswork that has limited the precision of other techniques. For hundreds of years, the clarity and ...

AIMED allows microscopes to image multiple depth layers simultaneously, producing detailed 3D reconstructions with reduced ...