THE major toxic effect of chloramphenicol is the production of bone-marrow arrest and aplastic anemia. Early in the development of chloramphenicol toxicity, vacuoles appear in the erythroid and ...

Purpose: Phenylketonuria (PKU) is an autosomal recessive disorder caused by mutations in the phenylalanine hydroxylase (PAH) gene. There have been more than 400 mutations identified in the PAH gene ...

Phenylalanine is an essential amino acid that carries out many important functions in the human body. The two types of phenylalanine are L-form and D-form. This article describes what phenylalanine is ...

To the Editor: The paper by Sherman et al. in the April 16 issue of the Journal indicating vacuolization of bone-marrow cells in an infant on a diet low in phenylalanine is a most important and ...

Phenylalanine is an amino acid in plant and animal foods, such as meat, eggs, fish, and soy products. It is safe for most people, except for those with phenylketonuria, who may not be able to break it ...