Two unique case reports highlight the diagnostic challenges and critical importance of comprehensive immunophenotyping in cases of T-cell acute lymphoblastic leukemia/lymphoma that present without ...
A team of researchers at the UC San Diego School of Medicine and Moores Cancer Center used genome technology to identify key markers of an aggressive type of leukemia, which may help pinpoint the ...
In some cases, the leukemia cells are resistant from the start. "Until now, there have been no predictive markers that can reliably predict a response to Venetoclax," says Andreas Trumpp, head of ...
Randomized study of prophylactic platelet transfusion threshold during induction therapy for adult acute leukemia: 10,000/microL versus 20,000/microL. TEL gene rearrangements due to the 12;21 ...
Chronic lymphocytic leukemia (CLL) is the most common leukemia in the Western world. New research published in the Journal of Leukocyte Biology reveals that certain protein markers may indicate which ...
You have full access to this article via your institution. Table 3 Rearrangements that indicate an ongoing rearrangement process during clonal switch either by a V–V replacement or N exchange by ...
HCL uniformly harbors a BRAF mutation that is not present in other B-cell malignancies. Hairy cell leukemia (HCL) is an indolent B-cell lymphoproliferative disorder that responds to several highly ...
Marker's Multi-Tumor-Associated Antigen Targeted (MultiTAA) platform is a novel, non-genetically modified cell therapy approach that selectively expands tumor-specific T cells from a patient's blood ...
A new study finds that children with B-cell precursor acute lymphoblastic leukemia (ALL) have an immune profile at birth that differs from matched controls. Although the cause of ALL remains unknown, ...
New research published today in JAMA Oncology reports how two separate DNA changes appear to predict aggressive childhood leukemias when they occur in combination. Over the course of a decade of work ...
Mixed phenotype acute leukemia has qualities of both lymphoid and myeloid leukemias. These mixed qualities make it very difficult to diagnose and treat. The outlook for people with this type of ...
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