Synthetic oligonucleotides have been used as critical research reagents in the biotechnology industry since its beginning in the 1970s. Their increasing use first led to the formation of many core ...

This is the final article in this series discussing HPLC oligonucleotide separations. This article will discuss LC/MS analysis of failure sequences, phosphorothioate modified siRNAs, CpG methylated ...

Music festivals concentrate higher-risk, polydrug-use behaviors than general populations, enabling efficient surveillance of ...

Liquid chromatography–mass spectrometry (LC-MS) was used to evaluate the stability of ethanol-free buprenorphine formulations in compounded oral syringes over 60 days. Chromatographic analysis showed ...

High-performance liquid chromatography-mass spectrometry (HPLC-MS) combines the separation power of LC with the detection specificity of MS. It has become an indispensable analytical tool in the ...

The sample throughput of high-sensitivity liquid chromatography-mass spectrometry (LC-MS) based proteomics analysis is restricted by the pressure limitations of LC and column hardware, with some ...

Novel biphenyl chromatography columns improve separation of structurally similar compounds, offering low UV interference, ...

Morphology and viability of isolated rat jejunal enterocytes: Enterocytes were separated from rat jejunum using EDTA-mediated calcium chelation and then stained with acridine orange (AO) to pinpoint ...

New users of the LC/MS laboratory and Sample Preparation Lab are required to engage in hands-on orientation to facility operations (e.g., laboratory access, scheduling, general use of equipment, ...