Isothermal Titration Calorimetry (ITC) remains the definitive technique for quantitatively assessing the thermodynamics of molecular interactions. By directly measuring heat changes during titrations, ...

All biochemical reactions involve recognition, binding, and the formation of noncovalent complexes. Many small molecule drugs act by selectively binding to protein or nucleic acid targets and altering ...

Our facility offers powerful analytical instrumentation used to study macromolecular interactions. We have instrumentation ideal for acquiring high quality kinetic, affinity and thermodynamic data for ...

Researchers need precise tools to measure molecular interactions and binding affinities for basic research and drug discovery. Conventional approaches such as isothermal calorimetry (ITC) present ...

Measuring Enzyme Kinetic Parameters with the ITC Universal Enzyme Assay Method Enzymes are important in drug discovery and development since they constitute approximately one-half of all known drug ...