Inflammatory bowel disease (IBD), encompassing Crohn’s disease and ulcerative colitis, remains a major clinical challenge owing to its complex pathophysiology and clinical management: it is a ...
IBD, inflammatory bowel disease. SCFA, Short-Chain Fatty Acids; LPS, Lipopolysaccharide; IL-6, Interleukin-6; IL-8, Interleukin-8; IL-10, Interleukin-10; IL-12 ...
Broad-spectrum antibiotics will alter the composition of the human gut microbiome, with transiently reduced bacterial diversity. Thus, it is reasonable to hypothesize that antibiotic-induced ...
Investigating the relationship between IL-1 and inflammation in inflammatory bowel disease (IBD), researchers unveiled mesenchyme homeobox 1 (MEOX1), an IL-1-dependent transcription factor that is ...
mTOR, mammalian target of rapamycin; p70S6K, The 70kDa ribosomal S6 kinase 1; NLRP3, NOD-like receptor thermal protein domain associated protein 3; ASC, apoptosis-associated speck-like protein ...
Despite an expanding therapeutic armamentarium, remission rates in inflammatory bowel disease (IBD) appear to plateau at 30–50% after 1 year of treatment, leading to the concept of a therapeutic ...
In patients with severe obesity, metabolic and bariatric surgery was linked to a lower risk for inflammatory bowel disease ...
Inflammatory bowel disease (IBD) encompasses a spectrum of disorders characterized by chronic inflammation of the digestive tract, driven in part by a dysregulated immune response to the gut ...
Inflammatory Bowel Disease (IBD), encompassing ulcerative colitis (UC) and Crohn's disease (CD), is a chronic inflammatory condition of the gastrointestinal tract with a rising global burden.
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