Obesity associated with hypothalamic dysfunction was initially described in patients with craniopharyngioma. Hypothalamic obesity may also result from brain radiation, infection (eg, tuberculosis), ...

Picking the Right Patient for Human Epidermal Growth Factor Receptor 3–Targeted Therapy in Platinum-Resistant Ovarian Cancer The Oncology Grand Rounds series is designed to place original reports ...

Hypothalamic obesity is a complex condition that doesn’t always respond to traditional weight loss methods. Medications, hormonal therapy, and surgery may be necessary to see results. Hypothalamic ...

This is due to epigenetic components: microRNA, histone and DNA methylation, gene mutations that alter the expression and production of the neurotrophic factor BDNF, which interacts with the receptors ...

A number of studies have reported an increased incidence of hypothalamic–pituitary dysfunction following traumatic brain injury or subarachnoid hemorrhage, and infections of the central nervous system ...

Please discuss the cause of ovulatory dysfunction in relation to subfertility. With anovulation, central defects (hypothalamic or pituitary) and ovarian failure have to be considered. Measurement of ...