Ochre Bio, a biotechnology company developing RNA therapeutics for chronic liver disease, today announced the successful completion of the research phase of its collaboration with GSK, delivering two ...

This article is based on a poster originally authored by Chris Bohl, Ken Brouwer, Karissa Cottier, Scott Heyward, Courtney Noah, Brian Ogilvie, and BioIVT. Several reports in the literature have ...

In vitro drug-metabolism data has been increasingly utilized in understanding and predicting pharmacokinetics in vivo. Traditionally, predictive studies have been conducted in animal models. Because ...

(A) Distinct phases of APAP-ALF. (B) Integrative multimodal approaches, including single-nucleus RNA sequencing spatial transcriptomics, four-dimensional intravital imaging and lineage tracing in both ...

Differentiated hepatocyte organoids formed networks of small canals that allowed bile acid to pass, in a manner similar to human tissue. While organoids aim to mimic human organs, the liver’s ...

The lab-made 3D liver model serves as a human relevant platform for analyzing the progressive stages of the liver disease, ...

What am I looking at? This is a single human hepatocyte. Its two nuclei are in blue (1). The other colors in this image are stains of the actin protein and are depth-coded, with red being the closest ...

Proper storage of CPHs is vital to ensure that they maintain their features. Cells should be stored below -150 °C in liquid nitrogen vapor. Cells stored in liquid nitrogen may cause liquid to enter ...

CHICAGO--(BUSINESS WIRE)--Celsis In Vitro Technologies (Celsis IVT), the pioneer and leader in hepatocyte technology, will host an industry-supported symposium as well as several poster presentations ...