NFL Week 13 picks, predictions, win probabilities for Packers-Lions, Rams-Panthers, Texans-Colts, Vikings-Seahawks, Raiders-Chargers, games this week.

NFL Week 13 picks, predictions for every NFL game this week, including Packers-Lions, Chiefs-Cowboys, Bengals-Ravens, Bears-Eagles, Bills-Steelers.

NFL Week 13, aka Thanksgiving weekend, is here, so let's look at the odds and make some picks and predictions for the coming weekend.

While the Philadelphia Eagles (8-3) still have control of the NFC East, things have tightened up a bit with the Dallas Cowboys (5-5-1) beating them last week. The Washington Commanders (3-8) and New York Giants (2-10) are still bringing up the rear and are more focused on their 2026 draft position at this point.

The National Weather Service's Climate Prediction Center says colder-than-normal weather is most likely in the northern and northeastern United States, but some forecasters say a complex dance involving the polar vortex could send some of the coldest weather on Earth toward the US.

Bryce Young is coming off a franchise-best 448-yard passing game and the Panthers are only a half-game behind the Buccaneers in the NFC South. Brock Purdy excelled in his return and the 49ers scored 41 points. The Niners need Purdy, Christian McCaffrey and George Kittle to keep producing to offset a depleted defense missing its two best players.