B-1 cells are innate-like B cells that have features of both the adaptive and the innate immune systems. The development of B-1 cells is distinct from that of conventional B-2 cells and leads to the ...
Type 1 diabetes is caused by insulin deficiency resulting from immune-mediated destruction of pancreatic beta cells. Its cause is multifactorial, with complex genetic factors and a strong influence of ...
The transcription factor AP-1 mediates gene regulation in response to a variety of extracellular stimuli including growth factors, cytokines, oncogenes, tumour promoters and chemical carcinogens ...
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