Focal adhesions are known as signalling platforms broadcasting the information of the biochemical and physical qualities of the extracellular matrix into intracellular signalling cascades. However, ...

This is a preview. Log in through your library . Abstract Fibroblast migration involves complex mechanical interactions with the underlying substrate. Although tight substrate contact at focal ...

Focal adhesions are known as signaling platforms broadcasting the information of the biochemical and physical qualities of the extracellular matrix into intracellular signaling cascades. However, ...

The 68-kD protein (paxillin) is a cytoskeletal component that localizes to the focal adhesions at the ends of actin stress fibers in chicken embryo fibroblasts. It is also present in the focal ...

“Cell migration is required and essential for metazoan development, tissue regeneration and repair, as well as in immune surveillance. Many diseases such as cancer, fibrosis, and inherited ...

Using a novel method that gives a readout of which proteins are in specific locations within cells, UT Southwestern Medical Center researchers have identified a protein that plays a key role in cell ...

The adhesion of a cell to a surface is essential for many cellular processes, including the cell cycle. This article will describe recent studies which have expanded our knowledge of the role of focal ...

Researchers at Kyoto University, Okinawa Institute of Science and Technology Graduate University (OIST), and Photron Limited in Japan have developed the world’s fastest camera capable of detecting ...

Researchers have developed one of the world's fastest cameras capable of detecting fluorescence from single molecules. Researchers at Kyoto University, Okinawa Institute of Science and Technology ...

“Our work with this camera will help scientists understand how cancer spreads and help develop new drugs for treating cancer,” says bio-imaging expert Takahiro Fujiwara, who led the research at the ...