This module explores the synthesis of amines with a focus on the reductive amination reaction. Numerous examples from the discovery and commercial manufacturing of pharmaceuticals are included. After ...

Some 60 g of (+)-discodermolide, a potent inhibitor of tumor cell growth, has been prepared in a 39-step synthesis by the Novartis Chemical & Analytical Development Group in Basel, Switzerland. The ...

Chemists have developed a straightforward method to convert common chemicals like carboxylic acids, alcohols, and alkanes directly into valuable alkenes. Chemists from the National University of ...

Hundreds of chemists can’t possibly share a 450-sq-ft lab—unless, that is, they don’t have to be there. Eli Lilly & Co. designed its Automated Synthesis Lab around this idea. Logging in from their ...

Chemical synthesis is already central to life and society, and has a fundamental role to play in delivering a sustainable future. The discovery, optimisation, and scalable manufacture of molecules and ...

Based on a symmetry-guided synthesis strategy, the research group of Professor Yefeng Tang at Tsinghua University recently ...

Professor Craig J. Hawker is Clarke Professor and holds the Alan and Ruth Heeger Chair of Interdisciplinary Science at UCSB where he directs the California Nanosystems Institute and the Dow Materials ...

With growing concerns over fossil fuel depletion and the environmental impacts of petrochemical production, scientists are ...