Chromosomal rearrangements, such as chromosome segment inversions, may affect the epigenetic landscape as well as gene expression. Different kinds of chromosome segment inversions have been found in ...
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After inversion by CRISPR/Cas, the epigenetic state of plant chromosomes remains stable
The epigenetic state of chromatin, gene activity, and chromosomal positions are interrelated. A research team from the IPK Leibniz Institute (IPK) and the Karlsruhe Institute of Technology (KIT) has ...
A novel approach that combines DNA template strand sequencing (Strand-seq) with a newly developed software package, Invert.R, can map and genotype putative inversions genome-wide in an untargeted ...
Balanced chromosome aberrations in leukemias following chemotherapy with DNA-topoisomerase II inhibitors. An inv(16)(p13q22) was observed in only two of 180 cases of t-MDS and t-AML in Copenhagen and ...
For decades, the Y chromosome – one of the two human sex chromosomes – has been notoriously challenging for the genomics community to sequence due to the complexity of its structure. Now, this elusive ...
A new application of the CRISPR/Cas molecular scissors promises progress in crop cultivation. Researchers have succeeded in modifying the sequence of genes on a chromosome using CRISPR/Cas. For the ...
Chromosomes are thread-like structures located inside the nucleus of animal and plant cells. Each chromosome is made of protein and a single molecule of deoxyribonucleic acid (DNA). Passed from ...
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