The 49ers had only 10 defenders on the field when Fred Warner's ankle injury occurred, and so much more went wrong en route to a 31-19 loss at

So far this season, starting quarterback Brock Purdy, tight end George Kittle, defensive end Nick Bosa and wide receivers Jauan Jennings, Ricky Pearsall and Brandon Aiyuk have all missed multiple games due to injury.

Dan Orlovsky pulls receipts on Mac Jones after San Francisco 49ers’ OT win over Los Angeles Rams, revisiting his two-year-old take.

The 49ers are to have both wide receiver Jauan Jennings and quarterback Mac Jones on the field against the Buccaneers in Week 6.

San Francisco 49ers quarterback Brock Purdy and wide receiver Ricky Pearsall reportedly have a "chance" to return vs. the Atlanta Falcons in Week 7.

Expert recap and game analysis of the Tampa Bay Buccaneers vs. San Francisco 49ers NFL game from 13 October 2025 on ESPN (IN).

Tampa Bay Buccaneers wide receiver Chris Godwin Jr. is not expected to play in Sunday's home game against the San Francisco 49ers because of a fibula injury, ESPN reported Friday. Godwin, 29, has six catches for 52 yards over the past two games after missing the first three weeks of the season while recovering from a dislocated left ankle last season that required multiple surgeries.