New guidelines recommend doctors tackle Crohn's disease head-on, calling for the use of cutting-edge drugs as early as possible to quell the autoimmune GI disorder as quickly as possible. The updated ...

Federal regulators approved a first-of-its-kind cholesterol medication from Merck that rivals the effectiveness of powerful ...

Each year, the FDA approves a wide range of medications that help shape the future of medicine in the U.S. These include novel drugs that offer new treatment options, as well as first generics and ...

Illustration of New Drug Application paperwork surrounded by pills, vials, and DNA. The US Food and Drug Administration approved 46 new molecular entities in 2025. Credit: C&EN/Shutterstock The year ...

First-in-class drugs can be highly innovative because of their novel mechanisms of action, but they also carry uncertainty in the absence of clinical experience. To understand how such drugs advance ...