Retrotransposon drives cancer by altering 3D genome structure

Scientists at St. Jude Children's Research Hospital have revealed previously unappreciated roles for the retrotransposon LINE ...
EurekAlert!

BMI1s interact with condensin complexes to regulate chromatin 3D structure and gene expression in Arabidopsis

This study is led by Dr. Yue Zhou (State Key Laboratory of Gene Function and Modulation Research, School of Advanced Agricultural Sciences, Peking-Tsinghua Center for Life Sciences, Peking University, ...
News Medical

First crystal structure of alternative DNA shape from the insulin gene revealed

The first crystal structure of an alternative DNA shape from the insulin gene has been revealed by a UCL-led research team. DNA is widely accepted to be formed of two strands that wind around one ...
Medical Xpress

Gene therapy for sickle cell and β-thalassemia works by disrupting three-dimensional genome structure

Scientists at St. Jude Children's Research Hospital and Northwestern University identified a previously unknown treatment opportunity for sickle cell disease and β-thalassemia. The discovery, ...
Science Daily

Structure of a eukaryotic CRISPR-Cas homolog, Fanzor2, shows its promise for gene editing

Scientists have revealed how Fanzor2's divergence from bacterial ancestors may make it a useful tool for future genomic engineering endeavors. A revolution in biomedicine is currently underway, driven ...
News Medical

Study reveals link between dyslexia genes and brain structure

Dyslexia is a common learning difficulty in which genes often play a role. How do genes associated with dyslexia relate to brain structure in the general population? In a large-scale study published ...