The first step in DNA replication requires the assembly of a group of proteins called the Origin Recognition Complex (ORC). Researchers have determined how the ORC assembles during the cell division ...

Unlike nuclear DNA, mitochondrial DNA (mtDNA) is circular in nature and organized as mitochondrial nucleoids comprised of DNA-protein complexes that are distributed in the matrix. It is also inherited ...

For the first time, scientists have witnessed the very moment DNA begins to unravel, revealing a necessary molecular event ...

Fruit flies make for stingy mothers, imparting only a portion of the genetic building blocks their offspring need to survive. The rest must be produced by the fertilized egg in its first few steps of ...

Visualizing and quantifying DNA replication dynamics in living human cells remains challenging. Here, a new super-resolution ...